Searchable abstracts of presentations at key conferences in endocrinology

ea0050p358 | Reproduction | SFEBES2017

Pregnancy, pre-eclampsia and vitamin D: a multi-scale mathematical approach

Beentjes Casper , Tamblyn Jennifer , Bayani Anahita , Davis Christopher , Dunster Joe , Mirams Gary , Taylor-King Jake , Jabbari Sara , Kilby Mark , Hewison Martin

Vitamin D deficiency during pregnancy has been linked to adverse pregnancy outcomes such as pre-eclampsia (PET), but continues to be defined by serum measurement of a single metabolite, 25-hydroxyvitamin (25(OH)D). To identify broader changes in vitamin D metabolism during normal and PET pregnancies we developed a mathematical model using a reduced reaction network for vitamin D metabolism that allows for complete parametrisation by multiple vitamin ...

ea0050p358 | Reproduction | SFEBES2017

Pregnancy, pre-eclampsia and vitamin D: a multi-scale mathematical approach

Beentjes Casper , Tamblyn Jennifer , Bayani Anahita , Davis Christopher , Dunster Joe , Mirams Gary , Taylor-King Jake , Jabbari Sara , Kilby Mark , Hewison Martin

Vitamin D deficiency during pregnancy has been linked to adverse pregnancy outcomes such as pre-eclampsia (PET), but continues to be defined by serum measurement of a single metabolite, 25-hydroxyvitamin (25(OH)D). To identify broader changes in vitamin D metabolism during normal and PET pregnancies we developed a mathematical model using a reduced reaction network for vitamin D metabolism that allows for complete parametrisation by multiple vitamin ...